Nail Fungal

Nail fungal infections, also known as onychomycosis, occur when fungi invade the nails, leading to discoloration, thickening, and crumbling of the nails. The most common causative agents are dermatophytes, particularly Trichophyton rubrum and Epidermophyton floccosum, as well as Candida species, such as Candida albicans, Candida glabrata, Candida parapsilosis, and Candida tropicalis.

Testing for nail fungal infections is important for several reasons:

1. Accurate Diagnosis: Nail fungal infections can be challenging to diagnose based solely on clinical symptoms. Laboratory tests help confirm the presence of fungal pathogens, allowing for a more accurate diagnosis.

2. Identification of Specific Pathogens: Different fungal species may require different treatment approaches. Testing helps identify the specific fungi causing the infection, allowing for targeted and effective antifungal therapy.

At V-Labs America, we offer a comprehensive panel for testing nail fungal infections, including:

Candida Species:

· Candida albicans

· Candida glabrata

· Candida parapsilosis

· Candida tropicalis

Dermatophyte Species:

· Trichophyton rubrum

· Epidermophyton floccosum

Antibiotic-Resistant Markers:

· KPC (Klebsiella pneumoniae Carbapenemase)

· CTX-M (Cefotaximase-Munich)

· NDM (New Delhi Metallo-beta-lactamase)

· QnrA and QnrS (Quinolone resistance genes)

· mecA (Methicillin resistance gene)

· sul1 and sul2 (Sulfonamide resistance genes)

· dfrA1 and DfrA5 (Dihydrofolate reductase genes)

· VanA and VanB (Vancomycin resistance genes)

This comprehensive testing approach ensures not only the identification of the fungal pathogens causing the nail infection but also provides information about antibiotic resistance markers. While antibiotics are not typically used to treat fungal infections, the inclusion of antibiotic resistance markers may be relevant in cases where bacterial co-infections are suspected or for overall patient health management.

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